In terms of histone modification, what will result in a greater rate of gene expression?...
BIOLOGY
SAT 2021
In terms of histone modification, what will result in a greater rate of gene expression?
- A. DNA methylation
- B. Histone acetylation
- C. Addition of 5' Terminal Cap
- D. Addition of 3' Poly A Tail
Correct Answer: B. Histone acetylation
Explanation
Histone acetylation is the process of adding acetyl groups to positively charged lysine groups of histones. This process loosens the histone which allows for an easier initiation of transcription, which will lead to greater gene expression. DNA methylation does the opposite by adding methyl groups to DNA and lowering the rate of transcription. Alternative RNA splicing deals with RNA having certain introns and exons spliced out in a manner that produces different strands of mRNA from the same template strand of RNA. Addition of 5
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